Bioactive Small Molecules
Medchemexpress LLC Pinolenic acid ethyl ester | 493015-74-0 | MFCD12912314 | ≥98.0% | 306.48 g·mol⁻1 | C20H34O2 | 5MG
Pinolenic acid ethyl ester is the ethyl ester derivative of pinolenic acid, a polyunsaturated fatty acid found in pine seed oils. It is supplied as a research reagent for biochemical and lipid metabolism studies where a more lipophilic form of the free acid is required.
- Ethyl ester of pinolenic acid (CAS 493015-74-0).
- Purity ≥98.0%.
- Molecular formula C20H34O2.
- Molecular weight 306.48 g·mol⁻1.
- Appearance colorless to light yellow liquid; density ≈0.893 g/cm³.
- Storage store at 4°C, protect from light; in solution -80°C (6 months) or -20°C (1 month).
- Typical pack sizes 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.
Medchemexpress LLC 2-Naphthalenemethanol | 1592-38-7 | MFCD00004074 | 158.20 | 1 ML
2-Naphthalenemethanol is the metabolite of the environmental pollutant 2-methylnaphthalene. It covalently binds to alveolar protein and induces pulmonary toxicity. This product is supplied as a 10 mM solution in DMSO and is intended for research use only.
- Formulated as a 10 mM solution in DMSO
- For research use only
- Store at -80°C for up to 6 months or -20°C for 1 month (in solvent)
AdipoGen PK150 (Sorafenib Analog) (1 mg)
Chemical. CAS: 2165324-62-7. Formula: C15H8ClF5N2O3. MW: 394.7. Analog of the anticancer drug sorafenib. PK150 is a potent antibiotic. It shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA), Vancomycin intermediate S. aureus (VISA) with MICs of 0.3, 0.3-1, 0.3 µM, respectively. PK150 did not induce in vitro resistance and shows oral bioavailability and in vivo efficacy. The mode of action includes the interference with menaquinone biosynthesis by inhibiting demethylmenaquinone methyltransferase and the stimulation of protein secretion by altering the activity of signal peptidase IB.
Medchemexpress LLC SEZ6/BSRP-C Mouse 50ug | 50ug
The SEZ6/BSRP-C protein contributes significantly to cell-to-cell recognition and neuronal membrane signaling playing a crucial role in fundamental processes of neural networks SEZ6/BSRP-C is particularly important in balancing dendritic elongation and branching which shapes the complex structure of neurons SEZ6/BSRP-C Protein Mouse (HEK293 His) is the recombinant mouse-derived SEZ6/BSRP-C protein expressed by HEK293 with C-His labeled tag
Cayman Chemical N-Acetylpuromycin, Purity: ≥98%, CAS: 22852-13-7, 5 mg
A non-ribotoxic form of puromycin; formed in puromycin-resistant S. alboniger that endogenously express puromycin-acetyltransferase
Medchemexpress LLC HY-106048 10mg Medchemexpress, Bredinin aglycone CAS:56973-26-3 Purity:>98%
Medchemexpress, HY-106048 10mg Bredinin aglycone CAS:56973-26-3 Bredinin aglycone (5-Hydroxy-1H-imidazole-4-carboxamide) is a purine nucleotide analogue. Bredinin aglycone can be used to examine the efficiency of catalysts for the preparation of purine nucleotide analogues. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Vevorisertib | 1416775-46-6 | 98.0% | C35H38N8O | 10MG
Vevorisertib is an orally active, selective pan-AKT serine/threonine kinase inhibitor provided for research use. It inhibits AKT1, AKT2, and AKT3 with low-nanomolar potency and is intended for in-vitro and preclinical studies; it is not for human use. The compound has formula C35H38N8O, molecular weight 586.73, and a reported purity of about 98%.
- Potent inhibition of AKT isoforms at low nanomolar concentrations.
- Suitable for in-vitro and preclinical cancer research.
- High chemical purity appropriate for biological testing.
- Well-characterized small-molecule with published identifiers and IUPAC name.
- Available in small pack sizes to support laboratory workflows.
Cayman Chemical p,p'-DDE, Purity: ≥98%, CAS: 72-55-9, 100 mg
A metabolite and degradation product of the pesticide DDT; accumulates in various fish and sediment surrounding a DDT manufacturing plant; inhibits estrogen binding to rtERs (IC50 = 8 µM); induces concentration-dependent secretion of estradiol by granulosa and theca cell co-cultures isolated from porcine ovarian follicles; induces concentration-dependent secretion of estradiol by granulosa and theca cell co-cultures isolated from porcine ovarian follicles; decreases ATP levels, the proportion of sperm with high mitochondrial membrane potential, and motility of human sperm in vitro from 50-100 µM
Cayman Chemical CCT241533 (hydrochloride), Purity: ≥98%, CAS: 1431697-96-9, 5 mg
A selective Chk2 inhibitor (IC50 = 3 nM); potentiates the cytotoxicity of the PARP inhibitors, rucaparib and olaparib
Cayman Chemical CRL-40,941, Purity: ≥98%, CAS: 90212-80-9, 5 mg
An analytical reference standard categorized as a nootropic; intended for research and forensic applications
TARGETMOL CHEMICALS INC ANATIBANT 2HCL 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Anatibant 2HCl is a small molecule bradykinin B2 receptor antagonist for the treatment of neurological disorders and may be used in the study of brain injury. purity: 99%
Cayman Chemical TP-0903, Purity: ≥98%, CAS: 1341200-45-0, 10 mg
An inhibitor of Axl (IC50 = 27 nM ); exhibits greater than 50% inhibition of 11 kinases, including MER, TYRO3, JAK2, ALK, and Abl1, in a panel of 75 kinases at 200 nM, with IC50 values of 3 and 12.4 nM for Aurora A and B, respectively; decreases the phosphorylation of Akt and Axl in GAS6-stimulated, serum-starved PSN-1 pancreatic cancer cells (EC50s = 305 and 222 nM, respectively); decreases cell viability (IC50 = 6 nM) and induces cell cycle arrest at the G2/M phase in PSN-1 cells at 30 nM; reduces the viability of CRC cell lines (IC50s = 4.5-123 nM); exhibits 69 and 44% tumor growth inhibition in an HCT116 mouse xenograft model and a K-Ras-mutant CRC PDX mouse model, respectively, at 40 mg/kg
Apexbio Technology LLC PCI-32765 (Ibrutinib) 936563-96-1 5mg
PCI-32765 (Ibrutinib) is a small-molecule inhibitor targeting Bruton s tyrosine kinase (BTK) a cytoplasmic kinase integral to B-cell receptor (BCR) signaling By covalently binding to BTK active sites PCI-32765 disrupts downstream signaling cascades essential for B-cell maturation and activation Dysfunction or inhibition of BTK correlates with impaired B-cell development and reduction in autoantibody production PCI-32765 is commonly utilized in biomedical research to explore BTK-dependent signaling pathways elucidate molecular mechanisms underlying B-cell mediated disorders and examine therapeutic potential in B-cell malignancies and autoimmune models
Medchemexpress LLC RGD (Trifluoroacetate) | 2378808-45-6 | 99.55% | 460.36 | 50 MG
RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines, elicits specific cell responses, and binds to integrins. It is the most effective and most often employed peptide sequence for stimulated cell adhesion on synthetic surfaces. For research use only.
- Effectively triggers cell adhesion
- Addresses certain cell lines
- Elicits specific cell responses
- Binds to integrins, including α3β1, α5β1, α8β1, αIIbβ3, αvβ1, αvβ3, αvβ5, αvβ6, αvβ8, and to some extent α2β1 and α4β1
- Suitable for laboratory centrifugation and storage
Apexbio Technology LLC BAY 87-2243, 50mg. Cas: 1227158-85-1 MFCD: MFCD28143915. HIF-1 inhibitor,potent and selective
BAY 87-2243 is a selective inhibitor of HIF-1 induced gene activation [1].In HCT-116 cells, BAY 87-2243 inhibits the hypoxia increased HRE-dependent luciferase expression with IC50 value of 0.7nM and inhibits the expression of HIF target gene CA9 with IC50 value of 2nM. Other sizes are available. Please inqury us for quote.